From 2D to 3D Crystals

A Multi-Scale, Multi-Technique and Multi-System Approach of the Crystallization of Organic Molecules

The occurrence of two or more crystal structures for a given molecule, a phenomenon which is called polymorphism, is ubiquitous to various classes of synthetic and natural compounds. Examples of polymorphism are known in numerous application fields, such as food, explosives, pigments, semiconductors, fertilizers, and pharmaceutical drugs. Different crystal structures, so-called polymorphs, of the same compound exhibit sometimes very different physical properties, chemical reactivity, and biological functions. For instance, the polymorphs might differ in solubility ruining the pharmaceutical effect of one or more of the polymorphs. Understanding and controlling polymorphism is therefore very important. Simple questions, such as "How many polymorphs has a given compound?" or "What drives polymorph selection?", remain unanswered yet. In this scientific context, scientists have started to explore the occurrence of substrate-induced polymorphism, i.e. the formation of polymorphs that exist only in the vicinity of solid substrates. In particular, 2Dto3D has the ambition to elucidate how positional and orientational order of molecules propagate from the substrate to the upper crystal layers. In this manner, 2Dto3D will gain a fundamental understanding of polymorphism at the interface with solid substrates.

The Network

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Steven De Feyter

Co-ordinator

Division of Molecular Imaging & Photonics,

Department of Chemistry,

KU Leuven-University of Leuven,

Celestijnenlaan 200F,

Leuven, Belgium-3001

Sandra Van Aert

Electron Microscopy for Materials Science (EMAT), University of Antwerp, Gronenborgerlaan 171,

Antwerp, Belgium-2020

Yves Geerts

Laboratory of Polymer Chemistry,

Faculty of Science,

Université Libre de Bruxelles (ULB),

CP206 / 1, Boulevard du Triomphe, 1050 Brussels, Belgium

Roland Resel

Institute of Solid State Physics, Graz University of Technology, A-8010 Graz, Austria

Roberto Lazzaroni

Laboratory for Chemistry of Novel Materials,

University of Mons,

Place du Parc 20, 7000 Mons, Belgium

Klaus Müllen

Max Planck Institute for polymer Research, Ackermannweg 10, D-55128 Mainz, Germany

Latest News

2dto3d website goes live!

First progress meeting at University of Mons

         December 6, 2018                                        

Kick-Off meeting in Leuven

            June 14, 2018                                        

Useful links

2Dto3D

This is the website of a consortium 2Dto3D funded by the EOS program jointly awarded by FWO and FNRS

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Contact us